The Saints dropped their second game of the season on Tuesday against Central Springs 47-44.
St. Ansgar held a 28-19 lead at half, but would give up 28 points and only score 16 in the second to fall to the Panthers.
Senior Elizabeth Jenkins, junior Molly Jenkins and freshman Hali Anderson all scored in the double digits with 16, 10 and 13 points respectively.
Elizabeth capped off a double-double performance with 10 total rebounds and added four blocks. Anderson had five assists and three steals.
The Saints hosted Osage on Tuesday, but scores were not available at press time. They will travel to North Butler on Friday.