Actress Jennifer Aniston, left, and actor Owen Wilson play with "Marley" the title dog on the press line at the premiere of the feature film "Marley & Me" in Los Angeles on Thursday, Dec. 11, 2008. (AP Photo/Dan Steinberg)

"Marley and Me"

Many will never forget the adorable Golden Lab Marley, who stole our hearts in the 2008 comedy-drama. In the movie, he was played by 18 different pups.